The links between immune system, infections and cancer are complex and far to be understood at the moment. The immune system plays a key role in cancer progression control, notably through the destruction of cancer cells. In addition, it has been observed that some infections increase cancer risk (e.g. HPV, HBV, HCV…), whereas others can be used as therapeutic agents (e.g. oncolytic viruses). In parasitic communities, the direct and indirect roles of numerous pathogens on cancer incidence and progression are unknown, as well as their interactions between them. Here, we aim to understand, at different scales, the roles of infectious diseases sensu lato on oncogenic dynamics, particularly through their impact on immune system.